Isoselective Ring-Opening Polymerization of rac-Lactide From Chiral Takemoto’s Organocatalysts: Elucidation of Stereocontrol.

Abstract

We report that both commercially available (R,R)- and (S,S) enantiomers of chiral thiourea-amine Takemoto’s organocatalysts promote efficient control and high isoselectivity at room temperature of the ring-opening polymerization (ROP) of racemic lactide by kinetic resolution, yielding highly isotactic, semi-crystalline and metal-free polylactide (PLA).

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